If you want glowing, hydrated skin, you’ve likely heard of both Polynucleotides and Profhilo. But which treatment suits you best?

If you’re looking to improve skin quality and achieve a smoother, more radiant complexion, you may have heard of Rejuran. Rejuran polynucleotides are a regenerative injectable treatment developed in South Korea and widely used in Korean aesthetic medicine to repair and rejuvenate the skin from within.
Unlike traditional skin boosters that focus mainly on hydration, Rejuran polynucleotides work at a cellular level to restore damaged skin. The treatment uses purified PDRN (polynucleotides derived from salmon DNA), which support tissue repair, reduce inflammation, and stimulate collagen production. Through small Rejuran injections, the treatment improves skin elasticity, hydration, and texture while strengthening the skin barrier.
Because Rejuran polynucleotides focus on regeneration, they are particularly effective for concerns such as fine lines, dull skin, enlarged pores, acne scarring, and fragile or thinning skin. The treatment can also be used on delicate areas such as the under-eye area, neck, and décolletage, where improving skin quality is often more beneficial than adding volume.
Results develop gradually as the skin repairs itself. Many patients notice improved hydration and brightness after the first treatment, with further improvements in elasticity, texture, and overall skin health over a series of sessions.
During your consultation at Simply Clinics, a practitioner will assess your skin concerns and recommend whether Rejuran polynucleotide treatment is suitable for you. A personalised treatment plan ensures the best results while supporting long-term skin rejuvenation and healthier-looking skin.
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