In modern aesthetic medicine, there are more treatments than ever available for improving skin quality and achieving a smoother, rejuvenated complexion. Among the most innovative options are Rejuran polynucleotides, a regenerative injectable treatment developed in South Korea and widely used in Korean skincare clinics. Available at Simply Clinics in London, Rejuran treatment focuses on repairing and strengthening the skin from within, helping to improve hydration, elasticity, and overall skin health. But how does Rejuran polynucleotide treatment compare to other popular aesthetic treatments like dermal fillers, anti-wrinkle injections, or PRP?
Are Rejuran Polynucleotides a Filler?
No, Rejuran polynucleotides are not dermal fillers. While both are injectable treatments, they work in very different ways. Rejuran injections use purified PDRN (polynucleotides derived from salmon DNA) to stimulate skin regeneration at a cellular level. Rather than adding volume, Rejuran focuses on improving skin quality, hydration, elasticity, and tissue repair. Dermal fillers, by contrast, are typically made from hyaluronic acid and are used to restore lost volume, contour the face, and fill deeper wrinkles. Because they target different concerns, Rejuran skin booster treatments and fillers can often be combined as part of a comprehensive facial rejuvenation plan.
Can Rejuran Be Used Around the Eyes?
Yes. Rejuran polynucleotides are particularly suitable for delicate areas such as the under-eye region, where improving skin quality is often more beneficial than adding volume. By stimulating collagen production and supporting skin repair, Rejuran injections can help improve fine lines, thin skin, and overall texture around the eyes, leading to a brighter, healthier-looking appearance.
Can Rejuran Be Combined With Anti-Wrinkle Treatments?
Yes, Rejuran treatment can be safely combined with anti-wrinkle injections because the treatments work in different ways. Anti-wrinkle treatments temporarily relax specific facial muscles to soften dynamic lines such as frown lines or crow’s feet. Rejuran polynucleotides, on the other hand, work within the skin to improve hydration, collagen production, and skin strength. Combining both treatments can provide a more comprehensive approach to facial rejuvenation, improving both expression lines and overall skin quality.
Are Rejuran Polynucleotides Derived From Salmon DNA?
Yes. Rejuran polynucleotides are derived from purified salmon DNA, specifically PDRN (polydeoxyribonucleotide). The DNA is carefully purified and processed to make it safe and biocompatible for aesthetic use. These regenerative molecules support tissue repair, collagen stimulation, and skin regeneration, helping to restore healthier, stronger skin over time. Although the origin may sound unusual, this technology is widely used in Korean aesthetic medicine and has become a popular treatment for improving skin quality and promoting natural-looking rejuvenation.

